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Introduction to RVO

Complications of RVO

RVO can lead to other issues, beyond macula edema. These are known as complications of the condition.

Complications of RVO include:1,2

  • Abnormal blood vessel formation triggered by the raised VEGF levels seen in macular oedema
  • Bleeds in the eye results from the formation of abnormal blood vessels which are prone to leaking
  • Glaucoma caused by the raised pressure in the eye, damaging the optic nerve
  • Retinal detachment from tissues that support it, caused by the abnormal vessel growth
4 boxes labelled 1 to 4 with arrows between them. The first box has an image of a blood vessel with arrows pointing away from it and the caption “RVO causes fluid build up: The swelling seen in the eye in RVO makes VEGF levels rise.”. The second box has blood vessels branching and the caption “Blood vessel formation: VEGF triggers abnormal blood vessel formation.”. The third box has a broken blood vessel and the caption “Bleeds and retinal detachment: the new vessels rupture, leaking blood, and also make the retina detach.”. The last box has a cross section of an eye with pressure written inside and the text “Glaucoma: the pressure eventually damages the optic nerve.”.

References

  1. Cleveland Clinic. Retinal Vein Occlusion (RVO) Available at: https://my.clevelandclinic.org/health/diseases/14206-retinal-vein-occlusion-rvo. Last accessed April 2025.
  2. NHS Foundation Trust. Retinal vein occlusion. Available at: https://www.yorkhospitals.nhs.uk/seecmsfile/?id=2333. Last accessed April 2025.