Desktop disease specific banner PBC 2x
Hormonal and Rare Conditions Primary Biliary Cholangitis Complications
Complications
About PBC

Complications

Advanced PBC can cause inflammation and fibrosis in the liver, which can lead to a variety of further complications such as decompensation and sometimes a need for liver transplant.1

The complications that arise from advanced PBC are wide-ranging but can include:2,3

A list of complications from advanced PBC. Osteoporosis (Bones become weak and brittle), vitamin deficiencies, portal hypertension (increased pressure of your abdominal blood vessels, ascites (build up of fluid in your stomach), liver failure, liver cancer.

References

  1. Poupon R. Primary biliary cirrhosis: a 2010 update. J Hepatol. 2010;52(5):745-758.
  2. NHS. Primary biliary cholangitis. Available at: https://www.nhs.uk/conditions/primary-biliary-cholangitis-pbc/. Last accessed April 2025.
  3. Mayo Clinic. Primary biliary cholangitis. Available at: https://www.mayoclinic.org/diseases-conditions/primary-biliary-cholangitis/symptoms-causes/syc-20376874. Last accessed April 2025.