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About Chronic Rhinosinusitis with Nasal Polyps (CRSwNP)

What causes CRSwNP?

It’s not fully understood what causes CRSwNP, but it is linked to long-term inflammation in your nasal passages and sinuses.

It is thought that your genetics (i.e. in your DNA), other associated health conditions (known as “co-morbidities”) and things you are exposed to in the environment may play a role in your chances of developing it.1

Several factors that increase your risk of getting nasal polyps are2,3

Graphic showing 5 boxes with risk factors and icons representing them. First is “Asthma” with an inhaler icon. Second is “Intolerance or sensitivity to some medicines” with a pill icon. Third is “Allergic rhinitis” with an icon of someone blowing their nose. Fourth is “Immunosuppression” with a medical mask icon. Fifth is “Chronic dental infection” with a tooth icon.

References

  1. Stevens WW, Schleimer RP and Kern RC. Chronic Rhinosinusitis with Nasal Polyps. Journal of Allergy and Clinical Immunology: In Practice. 2016 Jul-Aug;4(4):565-72.
  2. NHS. Nasal polyps. Available at: https://www.nhs.uk/conditions/nasal-polyps/. Last accessed April 2025.
  3. Min JY, Tan BK. Risk Factors For Chronic Rhinosinusitis. Current opinion in allergy and clinical immunology. 2015 Feb 1;15(1):1–13.